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Solutions for Peripheral Nerve Injuries

Surgeons at Florida Orthopaedic Institute are pioneering nerve repairs with new products from AxoGen®.

Over 1.4 million Americans experience a peripheral nerve injury each year. Nearly 900,000 require surgical intervention. In the past, surgeons have used the patient’s own nerves from another part of their body to repair the damage. But additional surgeries cost more, take more time and have physical shortfalls.

Florida Orthopaedic Institute surgeons are using three cutting-edge AxoGen products:


Avance Nerve Graft is a readily available human nerve tissue graft (allograft) for surgical repair of peripheral nerve breaks. AxoGen recovers human peripheral nerve tissue and cleans cellular and noncellular debris through a proprietary cleansing process.

AxoGen nerve pain treatment

Avance Nerve Graft provides a 3-dimensional framework for bridging a nerve gap, and its extracellular matrix remodels into a patient’s tissue. There’s no need for the patient to have donor nerve surgery, so no negatives are associated with an additional surgical site.


AxoGuard Nerve Connector is the only porcine submucosa (a type of thin layer of tissue) extracellular matrix (ECM) that helps draw together cut or severed peripheral nerves without tension.

AxoGen AxoGen nerve pain treatment

AxoGuard Nerve Connector aligns and connects severed nerve ends with less than a 5 mm gap (the width of two nickels and one penny). The ECM material allows the body’s natural healing process to repair the nerve by isolating and protecting it during the healing process. The patient’s cells merge into the ECM to form a tissue similar to the nerve epineurium (the outermost layer of dense connective tissue surrounding a peripheral nerve).


AxoGuard Nerve Protector protects injured nerves and reinforces the nerve reconstruction while preventing soft tissue attachments. The AxoGuard multi-laminar extracellular matrix (ECM) is designed to protect and isolate, separating and protecting the nerve from surrounding tissues during the healing process. Like the AxoGuard Nerve Connector, patient cells integrate into the surgical implant to form a nerve surrounding tissue.


If you have damaged or compressed nerves, consults with one of the surgeons below to see if one of AxoGen’s products can help with peripheral nerve reconstruction. Talk with your Florida Orthopaedic Instiute physician for nerve pain treatment.

Success Stories

Learn more about nerve repair by watching the videos in our gallery.

Briant Cummings, Hand Replant Testimonial

April 4, 2018

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