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Physicians Sayed M. Zaffer, M.D.

Syed M. Zaffer, M.D.

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My passion is to improve the quality of life of my patients by offering them evidence-based treatment choices to better manage their pain and functional limitations.

Dr. Zaffer is fellowship trained and board certified in physical medicine and rehabilitation by the American Board of Physical Medicine and Rehabilitation and in electromyography by the American Board of Neuromuscular and Electrodiagnostic Medicine. A physiatrist with more than 16 years of pain management and rehabilitation experience, Dr. Zaffer utilizes his extensive knowledge to educate patients about the options available, including treatment with non-surgical and interventional pain techniques.

Prior to joining Florida Orthopaedic Institute, Dr. Zaffer was the medical director of a private practice in outpatient physical medicine and rehabilitation as well as in electrodiagnostic medicine. He has focused on treating patients with physiatric conditions for over 12 years. As an expert in the field of pain medicine, Dr. Zaffer was a guest lecturer at Indiana University, speaking on topics pertaining to Physical Medicine techniques and treatment for rehabilitation patients. Dr. Zaffer has authored articles in the American Journal of Physical Medicine and the Clinical Journal of Sports Medicine, along with clinical research studies in neuropathy and sclerosis.

Dr. Zaffer studied medicine at Osmania University in India and pursued his passion for physical medicine and rehabilitation at Indiana University. He taught at Loyola University Medical Center in the Department of Orthopaedic Surgery and Rehabilitation. Dr. Zaffer is a member of the American Academy of Neuromuscular & Electrodiagnostic Medicine, the American Academy of Physical Medicine and Rehabilitation, and the American Society of Bariatric Physicians.

In his free time, Dr. Zaffer enjoys spending time with his family, hiking and reading.


Dr. Zaffer has been amazing. I came to him two years ago. He isolated the multiple issues with my foot and referred me for post trauma surgery on my foot. I have had two surgeries and am now being treated for neuropathy. He has been encouraging throughout all the pain and long recovery. If not for his patience and care I would still be struggling with chronic pain syndrome which I have had for four years.

Cheryl H.

Dr. Zaffer is a great doctor. He takes his time and answers all questions we might have. So far, there has not been much of a wait time to be seen. We are usually in and out within an hour.

Healthgrades Review

Dr. Zaffer has been my pain management physician for about two years. I have had two back surgeries and a full shoulder replacement reversal surgery. I absolutely could not have gotten through these surgeries without his help and expertise. He is professional, listens to his patients’ situations and gives them encouragement and hope to be able to live a better way of life through his knowledge and treatment. I truly value and recommend Dr. Zaffer.

Evalon B.

A blessing to have Dr. Zaffer as part of my team of doctors at Florida Orthopaedic Institute for the last two years. Thanks!

K. Orthner

Doctor Zaffer is the best!

UCompareHealthcare Review

If I could give him six stars, I would! I was courteously greeted when I entered the office and was seen shortly after arrival at each visit which made me feel that my time was valuable. Dr. Zaffer LISTENED to me and explored my issue. He worked WITH me to determine my plan of care. My pain is finally under control because of our TEAM effort. This practice should be a model for other offices! Thank you!


“Dr. Zaffer is a great doctor who listens and treats you like a person, not just another medical case. I really appreciate him.”

Patient Survey


  • Fellowship, Electromyography/Neuromuscular Diseases, Cleveland Clinic Foundation
  • Residency, Department of Physical Medicine & Rehabilitation, Indiana University School of Medicine
  • Transitional Internship, Indiana University School of Medicine/Community Hospital
  • Medical Degree, Deccan College of Medical Sciences, Osmania University, Hyderabad, India

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